Implication of Wnt signaling in neuronal polarization.
نویسندگان
چکیده
Wnt ligands comprise a large family of secreted glycoproteins that control a variety of developmental processes including cell polarization in diverse organisms. Through various receptors present on receiving cells, Wnts initiate intracellular signaling cascades resulting in changes in gene transcription or cytoskeleton reorganization. Recently, several lines of evidence have suggested the role of Wnt signaling in establishing axon-dendrite polarity in developing neurons. In this review, we summarize the recent results related with the role of Wnt signaling in neuronal polarization.
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ورودعنوان ژورنال:
- Developmental neurobiology
دوره 71 6 شماره
صفحات -
تاریخ انتشار 2011